On average, how many times per year does human skin replace itself?

Human skin undergoes a continuous process of regeneration, replacing itself approximately once every 28 to 30 days. This process means that, over the course of a year, skin effectively regenerates about 12 times.

This average may vary based on factors such as age, health, and environmental conditions, but the general consensus in biological studies supports the notion that the skin turnover rate leads to about a dozen complete cycles of replacement each year. Therefore, the correct answer reflects this well-established understanding of skin regeneration cycles in humans.